$100.00
10mg – Lyophilized *MUST BE RECONSTITUTED FOR RESEARCH APPLICATIONS*
SS-31 10mg (Elamipretide) is an advanced, high-purity synthetic aromatic-cationic tetrapeptide engineered to study inner mitochondrial membrane restoration, cardiolipin matrix stabilization, and cellular bioenergetics. By selectively targeting cardiolipin to optimize electron transport chain (ETC) kinetics and suppress the production of mitochondrial reactive oxygen species (ROS), this stable 10mg presentation stands as an elite investigative tool for tracking ischemia-reperfusion boundaries, tissue-level oxidative stress mitigation, and cellular longevity signaling in laboratory models.
Supplied as a stable, premium-grade lyophilized powder in a single 10mg vial. Restricted strictly to laboratory and in vitro evaluation.
Eterna Peptides presents premium-grade SS-31 (10mg) lyophilized powder, an elite presentation of the mitochondrial-targeted tetrapeptide Elamipretide (D-Arg-Dmt-Lys-Phe-NH2). Characterized by its unique alternating aromatic-cationic structural motif, SS-31 effortlessly bypasses non-selective cellular membranes to accumulate specifically within the inner mitochondrial membrane (IMM). Available in a precisely calibrated 10mg single-vial format, this premium compound serves as a premier investigative tool for tracking the optimization of electron transport chain kinetics, stabilization of cardiolipin matrices, and the mitigation of acute oxidative stress in laboratory models.
### Mechanism of Action
SS-31 operates as a highly specialized metabolic stabilizer via unique structural and biophysical interactions:
* **Cardiolipin Matrix Stabilization:** SS-31 binds selectively to cardiolipin, an essential polyunsaturated phospholipid exclusive to the inner mitochondrial membrane. By forming a protective electrostatic/hydrophobic cluster, it prevents cardiolipin from undergoing lipid peroxidation, preserving the foundational structural curvature and cristae architecture of the mitochondrion.
* **Electron Transport Chain (ETC) Optimization:** By stabilizing the cardiolipin microenvironment, SS-31 restores structural alignment between Complexes I, II, III, and IV, alongside Cytochrome c. This optimization facilitates efficient electron transfer, maximizing Adenosine Triphosphate ($ATP$) synthesis efficiency while drastically reducing electron leakage.
* **Superoxide Dissipation & ROS Mitigation:** Preclinical research shows that SS-31 directly downregulates the intracellular production of damaging reactive oxygen species ($ROS$) at its primary source. It curtails mitochondrial permeability transition pore (mPTP) opening curves, protecting cells from initiating premature apoptotic cascades.
* **Ischemia-Reperfusion Boundary Protection:** In tissue trauma modeling, SS-31 signaling is tracked for its capacity to accelerate microvascular recovery and shield fragile renal, cardiac, and neural cells from severe oxidative damage during simulated oxygen deprivation and subsequent reoxygenation phases.
### Research Applications
In preclinical and in vitro laboratory models, SS-31 10mg vials are actively utilized to investigate:
* Advanced mitochondrial biogenesis, inner membrane structural restoration, and cellular ATP synthesis kinetics.
* Intracellular ROS mitigation, lipid peroxidation prevention, and cellular senescence delays.
* Ischemia-reperfusion injury modeling across cardiorenal, pulmonary, and cerebrovascular tissue matrices.
* Neurodegenerative pathway resilience, microglial inflammatory modulation, and age-related mitochondrial decay deceleration.
Our SS-31 vials undergo strict laboratory stabilization, high-grade purification, and uniform vacuum-drying guidelines to ensure absolute structural purity, rapid dissolution kinetics, and dependable experimental reproducibility.
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*Disclaimer: This product is sold strictly for laboratory research and development use only. It is not intended for human consumption, diagnostic, or therapeutic purposes.*
