$75.00
10mg – Lyophilized *MUST BE RECONSTITUTED*
KPV is a peptide recognized for its anti-inflammatory and immunomodulatory properties. It is particularly useful in studies exploring inflammatory pathways and immune response mechanisms.
10mg – Lyophilized *MUST BE RECONSTITUTED FOR RESEARCH APPLICATIONS*
KPV 10mg (Lysine-Proline-Valine) is a premium, high-purity synthetic tripeptide fragment derived from alpha-MSH, engineered to study potent anti-inflammatory, immunomodulatory, and cellular barrier restoration cascades. By directly inhibiting NF-kB nuclear translocation and suppressing pro-inflammatory cytokine expression without inducing melanogenesis, this stable 10mg formulation stands as a premier investigative tool for tracking mucosal lining repair, structural fibroblast balancing, and tissue-level stress mitigation in laboratory models.
Supplied as a stable, premium-grade lyophilized powder in a single 10mg vial. Restricted strictly to laboratory and in vitro evaluation.
Eterna Peptides presents premium-grade KPV (10mg) lyophilized powder, an advanced synthetic tripeptide composed of the amino acid sequence Lysine-Proline-Valine. Structurally modeled after the C-terminal fragment of Alpha-Melanocyte Stimulating Hormone (α-MSH), KPV is a non-lenticular signaling molecule heavily investigated for its profound anti-inflammatory, antimicrobial, and immunomodulatory properties without triggering melanogenesis. This precise 10mg formulation serves as an elite investigative tool for exploring cellular barrier restoration and targeted cytokine suppression.
### Mechanism of Action
KPV operates through direct cellular and nuclear pathways to modulate inflammatory stress states:
* **NF-kB Pathway Downregulation:** Research indicates KPV enters target cells via specialized transporter mechanisms where it directly inhibits the translocation and activation of Nuclear Factor Kappa B (NF-kB). By turning off this master inflammatory switch, it downregulates the downstream transcription of pro-inflammatory cytokines, including TNF-alpha, IL-1 beta, and IL-6.
* **Intestinal & Mucosal Barrier Stabilization:** In inflammatory models, KPV is observed tracking the preservation of enterocyte structural integrity, upregulating tight junction protein expressions, and mitigating lumen stress profiles.
* **Wound Healing & Structural Remodeling:** It interacts closely with structural fibroblasts to modulate collagen deposition mechanics. Preclinical evaluation suggests KPV balances early-stage inflammation to promote clean, hyperplastic tissue remodeling while minimizing atypical scar formation.
* **Antimicrobial Synergy:** Beyond purely systemic immune mechanics, the structural architecture of KPV has been investigated for its direct cell-wall disrupting behaviors against specific bacterial and fungal pathogens, such as Candida albicans.
### Research Applications
In preclinical and in vitro laboratory models, KPV 10mg vials are actively utilized to investigate:
* Localized and systemic inflammatory responses, colitis/IBD cellular trauma, and mucosal layer repair mechanics.
* Advanced dermatological cell tracking, psoriasis/dermatitis stress models, and epidermal barrier homeostasis.
* Accelerated soft tissue wound healing, collagen cross-linking kinetics, and fibroblastic structural balancing.
* The comparative baseline potency and safety profiles of non-melanotropic alpha-MSH derivatives.
Our KPV vials undergo strict laboratory stabilization, purification, and vacuum-drying guidelines to ensure absolute structural purity, rapid dissolution kinetics, and dependable experimental reproducibility.
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*Disclaimer: This product is sold strictly for laboratory research and development use only. It is not intended for human consumption, diagnostic, or therapeutic purposes.*
