$150.00
Cagrilintide is a long-acting amylin analogue designed to support weight management by enhancing satiety and reducing food intake. It works synergistically with GLP-1 receptor agonists to improve metabolic regulation. Currently being studied for its potential in treating obesity and metabolic disorders, Cagrilintide offers a promising approach to appetite control and weight loss.
Cagrilintide 10mg is a high-purity synthetic, acylated amylin analogue designed to study homeostatic satiety signaling, delayed gastric emptying, and multi-pathway metabolic regulation. By acting as a non-selective amylin receptor agonist, it serves as a premier investigative tool for tracking synergistic adipose tissue reduction and appetite suppression when evaluated alongside GLP-1 receptor agonists in laboratory models.
Supplied as a stable, premium-grade lyophilized powder in a 10mg vial. *MUST BE RECONSTITUTED FOR RESEARCH APPLICATIONS.* Restricted strictly to laboratory and in vitro evaluation.
Eterna Peptides presents premium-grade Cagrilintide (10mg) lyophilized powder, a highly purified synthetic acylated amylin analogue. As a non-selective amylin receptor agonist ($AMY$), Cagrilintide is a core compound utilized in advanced metabolic research to study homeostatic appetite regulation, delayed gastric emptying, and multi-pathway weight management synergy.
Mechanism of Action
Cagrilintide operates via distinct neuroendocrine pathways to modulate metabolic signaling and energy balance:
* **Amylin Receptor Agonism:** It acts as a potent agonist at all three amylin receptor subtypes ($AMY_1$, $AMY_2$, and $AMY_3$) as well as calcitonin receptors, projecting directly to the area postrema in the hindbrain to mediate sustained satiety signals.
* **Synergistic Co-Activation:** In metabolic modeling, it is heavily researched alongside GLP-1 receptor agonists (such as Semaglutide or Tirzepatide). Because amylin signaling operates independently of the incretin pathway, combining these mechanisms explores a dual-braking system on appetite centers.
* **Gastric Kinetics:** It aids in tracking the rate of gastric emptying and glucagon secretion regulation, exploring pathways that stabilize postprandial glucose fluctuations.
* **Acylation Stability:** The structural acylation of the peptide chain significantly increases its resistance to enzymatic degradation, extending its experimental half-life in laboratory models.
Research Applications
In preclinical and in vitro laboratory models, Cagrilintide 10mg is extensively investigated to study:
* High-velocity adipose tissue reduction and the mechanics of long-term energy expenditure optimization.
* Homeostatic satiety signaling and the neurochemical suppression of food intake.
* Combined incretin/amylin receptor saturation kinetics in obesity and metabolic disorder models.
* Glucagon suppression pathways and insulin sensitivity adaptations.
Our Cagrilintide vials are manufactured under strict quality control standards to guarantee absolute structural purity, rapid reconstitution capabilities, and exceptional analytical consistency across all research setups.
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*Disclaimer: This product is sold strictly for laboratory research and development use only. It is not intended for human consumption, diagnostic, or therapeutic purposes.*
