$250.00
175mg Total Active Mass per Capsule — 60 Capsules per Bottle
Thermox Capsules 175mg is an ultimate-tier, oral small-molecule research matrix pairing BAM-15 (10mg), C15 Pentadecanoic Acid (150mg), and SLU-PP-332 (15mg) to study accelerated non-stimulatory thermogenesis, exercise-mimicry signaling, and cellular membrane optimization. By concurrently inducing proton uncoupling at the inner mitochondrial membrane, activating nuclear ERRα/ERRγ pathways to drive PGC-1α mitochondrial biogenesis, and integrating odd-chain saturated lipids into cellular bilayers for structural stabilization, this precisely standardized 60-capsule presentation stands as a premier investigative tool for tracking rapid lipid beta-oxidation, white adipose browning kinetics, and lean tissue preservation in laboratory models.
Supplied as stable, precisely standardized oral research capsules (60-count). Restricted strictly to laboratory and in vitro evaluation.
Eterna Peptides presents premium-grade Thermox Capsules (175mg / 60 Capsules), a state-of-the-art multi-pathway research formulation engineered to evaluate accelerated mitochondrial uncoupling, nuclear receptor transcription, and systemic lipid beta-oxidation. Delivering a massive 175mg total active mass per capsule across a 60-capsule presentation, this highly advanced matrix integrates three distinct metabolic modifiers: the targeted mitochondrial uncoupler BAM-15 (10mg), the essential odd-chain longevity lipid C15:0 (150mg), and the exercise-mimetic ERRα/ERRγ agonist SLU-PP-332 (15mg). This synergistic combination provides researchers with a pristine, non-stimulatory model for tracking rapid white adipose tissue browning, adenosine triphosphate (ATP) turnover adaptations, and cellular membrane stabilization during longitudinal metabolic stress testing.
### Advanced 175mg Multi-Pathway Ingredient Breakdown
Each precisely standardized oral capsule is calibrated to deliver a highly bioavailable, uniform structural distribution of raw research compounds:
* **BAM-15 (10mg):** N5,N6-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine. A highly selective, small-molecule mitochondrial uncoupler that dissipates the inner mitochondrial membrane proton gradient without disrupting plasma membrane potential.
* **C15:0 Pentadecanoic Acid (150mg):** A high-purity, odd-chain saturated fatty acid increasingly recognized as an essential cellular longevity nutrient. It directly integrates into phospholipid bilayers to study structural resilience and combat cellular senescence curves.
* **SLU-PP-332 (15mg):** A novel small-molecule nuclear receptor agonist that selectively targets Estrogen-Related Receptors (ERRα, ERRβ, and ERRγ), acting as a potent exercise mimetic that drives transcription shifts independent of physical contraction models.
### Mechanism of Action
The Thermox 175mg matrix targets specific mitochondrial, nuclear, and structural checkpoints to explore advanced tissue-level repartitioning and cellular longevity:
* **Selective Mitochondrial Proton Uncoupling:** BAM-15 acts as a mitochondrial protonophore, safely carrying protons ($H^+$) across the inner mitochondrial membrane while bypassing the ATP synthase ($F_1F_0\text{-ATPase}$) motor. This action uncouples the electron transport chain from ATP synthesis, forcing the cell to heavily accelerate lipid oxidation to fulfill energy demands, converting the dissipated energy directly into non-shivering thermogenesis.
* **Nuclear ERRα/ERRγ Activation & PGC-1α Firing:** SLU-PP-332 binds to orphan nuclear receptors ERRα and ERRγ, upregulating the transcription of Peroxisome proliferator-activated receptor gamma coactivator 1-alpha ($PGC\text{-}1\alpha$). This master control cascade drives the synthesis of high-density mitochondrial networks in skeletal muscle and white adipose arrays, modeling the mechanics of active tissue browning.
* **Cellular Membrane Stabilization & Antifibrotic Defense:** C15:0 integrates into the fluid lipid membranes of cells, increasing structural turgor and decreasing fragility by up to 80%. This helps counter the physical stresses caused by rapid thermogenic flux, upregulating dynamic cellular recovery while protecting organelle integrity.
* **CPT-1 Transport & Fast-Twitch Muscle Repartitioning:** Concurrently, the combined signaling cascades upregulate Carnitine Palmitoyltransferase-1 ($CPT\text{-}1$) and pyruvate dehydrogenase kinase 4 ($PDK4$). This shifts cellular preference completely toward lipid clearance while promoting a structural adaptation toward oxidative, fatigue-resistant Type I skeletal muscle fiber profiles.
### Research Applications
In preclinical and in vitro laboratory models, Thermox Capsules 175mg are actively utilized to investigate:
* High-velocity lipid mobilization, visceral adipose tissue browning, and non-shivering thermogenic heat-dissipation curves.
* Orphan nuclear receptor ERR transcriptomics, PGC-1alpha upregulation, and exercise-mimicry signaling kinetics.
* Mitochondrial uncoupling mechanics, respiratory control ratios, and cellular oxygen consumption rates ($OCR$).
* Cellular membrane fluid dynamics, pentadecanoic acid lipid bilayer insertion, and protection against metabolic-induced cellular senescence.
Our Thermox Capsules undergo strict laboratory verification, multi-stage filtration, and precise mass encapsulation protocols to ensure absolute compound standardization, uncompromised molecular stability, and dependable experimental reproducibility across all 60 capsules.
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*Disclaimer: This product is sold strictly for laboratory research and development use only. It is not intended for human consumption, diagnostic, or therapeutic purposes.*
