$125.00
1mg – Lyophilized *MUST BE RECONSTITUTED*
Introducing IGF-1 LR3 – a synthetic, modified version of insulin-like growth factor-1, designed for extended activity. Research indicates that IGF-1 LR3 can stimulate cell division and growth, boost fat metabolism, and promote muscle repair and hypertrophy by inhibiting myostatin. Recent studies also suggest its potential utility in improving lactation in mothers with young offspring. Ideal for research applications, IGF-1 LR3 provides a valuable tool for exploring advanced therapeutic strategies in cellular growth and metabolic regulation.
1mg – Lyophilized *MUST BE RECONSTITUTED FOR RESEARCH APPLICATIONS*
IGF-LR3 1mg (Long Arg3 Insulin-like Growth Factor-1) is a premium, high-purity synthetic analogue engineered to study advanced cellular proliferation, skeletal muscle hypertrophy, and PI3K/Akt/mTOR pathway signaling. Modified structurally to bypass IGFBP neutralization and extend its active half-life, this precise 1mg formulation stands as a premier investigative tool for tracking satellite cell activation, myoblast differentiation, and structural muscle repair in laboratory models.
Supplied as a stable, premium-grade lyophilized powder in a single 1mg vial. Restricted strictly to laboratory and in vitro evaluation.
Eterna Peptides presents premium-grade IGF-1 LR3 (1mg) lyophilized powder, an advanced synthetic analogue of human Insulin-like Growth Factor-1. Specially modified by substituting a glutamic acid for an arginine at position 3 and adding a 13-amino-acid extension at the N-terminus, IGF-1 LR3 is engineered for significantly extended half-life and potency, making it an elite investigative tool for studying cellular proliferation, muscle hypertrophy, and tissue repair dynamics.
### Mechanism of Action
IGF-1 LR3 operates as a highly potent modulator of cellular growth and metabolic signaling:
* **Extended Half-Life Kinetics:** Unlike native IGF-1, which is rapidly neutralized by binding to insulin-like growth factor-binding proteins (IGFBPs), the structural modifications in IGF-1 LR3 drastically reduce its affinity for these proteins. This allows a much higher concentration of free peptide to remain active in the experimental medium for prolonged durations.
* **Hypertrophy and Myogenesis:** Research demonstrates that IGF-1 LR3 binds directly to the IGF-1 receptor (IGF-1R), triggering downstream PI3K/Akt/mTOR signaling pathways. This cascade drives skeletal muscle cell proliferation, myoblast differentiation, and muscular hypertrophy by stimulating local amino acid transport.
* **Myostatin Inhibition Support:** Preclinical models indicate that active IGF-1 signaling can counter myostatin pathways, tracking the acceleration of myofibrillar repair and mitigating muscle-wasting cellular deficits.
* **Nutrient Repartitioning:** It influences glucose and fatty acid metabolism, promoting cellular nutrient uptake into skeletal muscle tissue rather than adipose tissue beds during active metabolic stress modeling.
### Research Applications
In preclinical and in vitro laboratory models, IGF-1 LR3 1mg vials are actively utilized to investigate:
* Advanced musculoskeletal cellular repair, myofibrillar protein synthesis, and hyperplastic fiber growth.
* Accelerated soft tissue recovery, satellite cell activation, and connective tissue structural profiling.
* Cellular metabolic repartitioning, glucose transport mechanics, and adipose tissue modulation.
* The comparative baseline potency and receptor affinity of modified growth factor analogues versus native proteins.
Our IGF-1 LR3 vials undergo strict laboratory quality control guidelines to ensure absolute structural purity, stable lyophilization, and dependable experimental reproducibility.
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*Disclaimer: This product is sold strictly for laboratory research and development use only. It is not intended for human consumption, diagnostic, or therapeutic purposes.*
